WebJan 5, 2024 · Gambogic acid, a traditional Chinese medicine, possesses many properties, especially in antitumor activity [8, 9]. Unfortunately, its phase III clinical trial was declared failure, putting a halt in its promotion as a therapeutic drug. WebJul 3, 2024 · Gambogic acid, a common traditional Chinese medicine and widely distributed throughout South China, Vietnam, Cambodia, and Thailand. It is prenylated xanthone which is the significant bioactive...
Gambogic acid - Wikipedia
WebApr 4, 2012 · Related toxicological studies demonstrated that the LD 50 of gambogic acid is 45–96 mg/kg in experiments using mice. Chronic toxicity studies in these animals indicated that gambogic acid did not affect their cardiovascular and respiratory functions [98] but, at high doses, it induced toxic effects in the liver and kidneys [99]. WebNov 18, 2024 · Lung cancer is a leading cause of cancer mortality worldwide, with a 5-year survival rate of less than 20%. Gambogic acid (GA) is a naturally occurring and potent anticancer agent that destroys tumor cells through multiple mechanisms. According to the literature, one of the most potent inhibitors of caspases and apoptosis currently known is … thibaut indian panel
Gambogic acid suppresses the pentose phosphate pathway by …
WebGambogic acid C38H44O8 CID 5353639 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … WebGamboge is used for cancer, constipation, infections of the intestines by parasites, and other conditions, but there is no good scientific evidence to support these uses. Using … WebThe IC50s of Gambogic Acid for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 uM, respectively. All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use. Gambogic Acid, CAS 2752-65-0. Please contact us for prices and availability for the specification of ... thibaut inc