2024 Ets homologous factor

Ets homologous factor

Author: iisf

August undefined, 2024

WebNov 20, 2014 · Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell types including those lining the respiratory system. … WebAnalysis of three SNPs at the CAT and EHF gene located within the region of maximum linkage showed that T1667T and C (-262)T markers of the CAT gene are strongly associated with the disease [12]. In the process of identifying senescence-associated genes, we found significant suppression of the ets homologous factor (EHF) in cancer cells in …

WikiGenes - EHF - ets homologous factor

WebETS homologous factor (EHF) plays a critical function in epithelial cell differentiation and proliferation. However, the roles of EHF in cancer remain largely unknown. In the present study, we investigated the expression levels, precise function and mechanism of EHF in colorectal carcinoma (CRC). Webets homologous factor; hEHF; Description From NCBI Gene: This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants ... tpl0395

EHF promotes colorectal carcinoma progression by activating …

WebMar 3, 2024 · The pivotal role of the pioneer TF Forkhead box A1 (FOXA1) (Paranjapye, Mutolo, Ebron et al., 2024) and of Ets homologous factor (EHF) (Fossum, Mutolo, Yang et al., 2014), in coordinating processes that maintain the integrity of the airway epithelial barrier and its response to injury were reported recently. WebPR:000006946 ETS homologous factor (term hierarchy) InterPro Domains. IPR000418 Ets domain. IPR046328 ETS family. IPR033071 ETS homologous factor, SAM Pointed domain. IPR003118 Pointed domain. IPR013761 Sterile alpha motif/pointed domain superfamily. IPR036390 Winged helix DNA-binding domain superfamily. WebJun 26, 2024 · The SNP rs315854959 was located near the ETS homologous factor (EHF). In addition, four significant SNPs associated with the coefficient of MDM were detected, which clustered within a 0.38-kb region in GGA2 (103.48 Mb). These SNPs were located near histamine receptor H3-like (HRH3L). thermosept sks sicherheitsdatenblatt

Identification of Transcription Factor-Gene Regulatory Network ... - PubMed

EHF is essential for epidermal and colonic epithelial ... - bioRxiv

Webwww.ncbi.nlm.nih.gov WebSep 6, 2024 · One of these, at chromosome 11p13, is an intergenic region between Ets homologous factor (EHF) and Apaf-1 interacting protein (APIP). Our goal was to determine the functional significance of this region, which being intergenic is probably regulatory. To identify cis-acting elements, we used DNase-seq and H3K4me1 and H3K27Ac ChIP-seq … thermosept sek sicherheitsdatenblattWebFeb 18, 2024 · EHF (ETS homology factor) is a transcription factor that is generally expressed in epithelial tissue and has been shown to play a role in a variety of human … tpl0401b

"WebDec 16, 2014 · Ets homologous factor (EHF) is an Ets family transcription factor expressed in many epithelial cell types including those lining the respiratory … " - Ets homologous factor

Ets homologous factor

The ETS family of oncogenic transcription factors in solid

WebEts homologous factor (EHF) is a key member of the transcription factor network that regulates gene expression in the airway epithelium in response to endogenous and exogenous stimuli. EHF, which has altered expression in inflammatory states, maps to the 5′ end of an intergenic region on Chr11p13 that is implicated as a modifier of cystic ... WebDec 21, 2024 · ETS homologous factor (EHF) is an important member of the ETS family and contributes to the pathogenesis of multiple malignant tumors. To date, whether EHF participates in the development of GC via the c-Met signaling pathway remains unclear. Aim: To investigate the role and mechanism of EHF in the occurrence and development of GC.

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WebETS homologous factor Gene EHF Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 300 Protein existence Evidence at transcript level …

WebJun 30, 2024 · Ets homologous factor (EHF) is a key member of the transcription factor network that regulates gene expression in the airway epithelium in response to … Webtransformation specific) homologous factor, EHF, is an emerging epithelium-specific transcription factor that plays a role in many human cancers [1]. All ETS family members …

WebJun 30, 2024 · Ets homologous factor (EHF) is a key member of the transcription factor network that regulates gene expression in the airway epithelium in response to … WebOverexpression of ETS‑homologous factor (EHF) in non‑small cell lung cancer (NSCLC) is associated with poor patient prognosis. To explore the mechanism of the effect of EHF in NSCLC, EHF expression was examined in NSCLC and its role in cell proliferation, invasion, cell cycle, and apoptosis of NSCLC cells was evaluated by overexpressing EHF and/or …

WebFeb 18, 2024 · The ETS (E26 transformation-specific or erythroblast transformation specific) homologous factor, EHF, is an emerging epithelium-specific transcription factor that plays a role in many human cancers [1].

WebEHF ETS homologous factor [Homo sapiens (human)] - Gene - NCBI NCBI Skip to main content Skip to navigation Resources All Resources Chemicals & Bioassays BioSystems … tpl012waWebThe transcription factor-gene regulatory network consisted of 871 interactions between 80 transcription factors and 716 DEGs. ETS homologous factor (EHF) was one of transcription factors that had high connectivity with DEGs and regulated CACNB4 in the network. Verification by qRT-PCR revealed that EHF, KRT6A and DSG3 were … tpl/0132WebApproximately 50% of prostate cancers are associated with gene fusions of the androgen-regulated gene TMPRSS2 to the oncogenic erythroblast transformation-specific (ETS) transcription factor ERG. The three-dimensional proximity of TMPRSS2 and ERG genes, in combination with DNA breaks, facilitates the formation of TMPRSS2-ERG gene fusions. tpl03-1a forever greenWebETS homologous factor (EHF), a member of E26 transformation specific (ETS) transcription factors, has been reported overexpressed in ovarian cancer. However, the molecular mechanism underlying the biological function of EHF in … thermosept sksWebMar 29, 2024 · Gene ID: 26298, updated on 8-Dec-2024 Summary This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial … thermosept xtraWebJun 28, 2024 · The Ets family of transcription factors regulates a wide range of developmental processes, and many members have been implicated cancer. For example, Ets homologous factor (EHF), an Ets factor expressed solely in epithelia, has been associated with the progression of various cancers, but investigations into its … thermosept x-traWebETS homologous factor is a protein that in humans is encoded by the EHF gene. This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be associated with asthma susceptibility. thermosept xtra ulotka